![]() ![]() ![]() ![]() The nuclear lamina is composed of fibrous proteins, lamins, which associate with each other to form filaments. The best understood of these events is depolymerization of the nuclear lamina-the meshwork of filaments underlying the nuclear membrane. In open mitosis, the nuclear envelope breaks down and then re-forms around the two sets of separated (more.)ĭisassembly of the nuclear envelope, which parallels a similar breakdown of the endoplasmic reticulum, involves changes in all three of its components: The nuclear membranes are fragmented into vesicles, the nuclear pore complexes dissociate, and the nuclear lamina depolymerizes. In closed mitosis, the nuclear envelope remains intact and chromosomes migrate to opposite poles of a spindle within the nucleus. ![]()
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